منابع مشابه
Is protein folding hierarchic ? I . Local structure and peptide folding
ALTHOUGH SYNTHETIC ANALOGS of proteins might be developed ultimately, Flory’s succinct statement accurately summarizes the remarkable behavior of globular proteins. Today, an intense search is being made for the principles that guide the folding process. Although the work began with experimental studies (see Box 1), it has become increasingly clear that these results cannot be interpreted succe...
متن کاملProtein Stability, Folding, Disaggregation and Etiology of Conformational Malfunctions
Estimation of protein stability is important for many reasons: first providing an understanding of the basic thermodynamics of the process of folding, protein engineering, and protein stability plays important role in biotechnology especially in food and protein drug design. Today, proteins are used in many branches, including industrial processes, pharmaceutical industry, and medical fields. A...
متن کاملThermodynamics of Protein Folding and Design
Key words Classification system and/or index terms (if any) Supplementary bibliographical information Language ISSN and key title ISBN Recipient's notes Number of pages Price Security classification Distribution by (name and address) I, the undersigned, being the copyright owner of the abstract of the above-mentioned dissertation, hereby grant to all reference sources the permission to publish ...
متن کاملImportance of Protein Folding Sequence-Structure-Function
Protein Structure Prediction (II): Fold Prediction “Understanding protein structure, function and dynamics ranks among the most challenging and fascinating problems faced by science today. Since the function of a protein is related to its three dimensional structure, manipulation of the latter by means of mutation in the protein sequence generates functional diversity. The keys that will help u...
متن کاملNetwork Structure of Protein Folding Pathways
The classical approach to protein folding inspired by statistical mechanics avoids the high dimensional structure of the conformation space by using effective coordinates. Here we introduce a network approach to capture the statistical properties of the structure of conformation spaces. Conformations are represented as nodes of the network, while links are transitions via elementary rotations a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Letters
سال: 1988
ISSN: 0014-5793
DOI: 10.1016/0014-5793(88)80261-8